By John S. Bradley, John D. Nelson et al. (eds.)
New twenty first Edition! This bestselling and common source on pediatric antimicrobial therapy offers fast entry to trustworthy, up to date options for remedy of all infectious illnesses in childrens.
Practical, evidence-based options from the specialists in antimicrobial therapy
- Developed by means of exotic editorial board
- Designed if you happen to look after young ones and are confronted with judgements each day
- New at-a-glance tables of bacterial and fungal pathogen susceptibilities to accepted antimicrobials
- New details on neonatal developmental pharmacology
- Includes therapy of parasitic infections and tropical medicine
- Updated tests in regards to the power of the advice and the extent of facts for remedy thoughts for significant infections
- Anti-infective drug directory, entire with formulations and dosages
- Antibiotic remedy for overweight children
- Antimicrobial prophylaxis/prevention of symptomatic infection
- Maximal grownup dosages and better dosages of a few antimicrobials widespread in children
Read Online or Download 2015 Nelson's Pediatric Antimicrobial Therapy PDF
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Extra info for 2015 Nelson's Pediatric Antimicrobial Therapy
Group A or B streptococci59 Penicillin G IV for ≥7–14 days (shorter course for superficial funisitis without invasive infection) (AII) Group A streptococcus usually causes “wet cord” without pus and with minimal erythema; single dose of benzathine penicillin IM adequate. Consultation with pediatric ID specialist is recommended for necrotizing fasciitis (AII). – S aureus58 MSSA: oxacillin/nafcillin IV, IM for ≥5–7 days (shorter course for superficial funisitis without invasive infection) (AIII) MRSA: vancomycin (AIII) Assess for bacteremia and other focus of infection.
Surgical drainage of pus (AIII); physical therapy may be needed (BIII). – Empiric therapy Nafcillin/oxacillin IV (or vancomycin if MRSA is a concern) AND cefotaxime or gentamicin IV, IM (AIII) – Coliform bacteria (eg, Escherichia coli, Klebsiella spp, Enterobacter spp) For E coli and Klebsiella: cefotaxime OR gentamicin OR ampicillin (if susceptible) (AIII). For Enterobacter, Serratia, or Citrobacter: ADD gentamicin IV, IM to cefotaxime or ceftriaxone, OR use cefepime or meropenem alone (AIII).
Desired serum concentrations, trough 2–6 µg/mL. q Starting dose if gestational age <35+0 wk and postnatal ≤14 days. See Table A HIV for zidovudine dosage after 2 weeks of age and for NVP and 3TC recommendations. n o p C. 5 mg/kg q24h (see Chapter 11). Desired serum concentrations: 20–35 mg/L (peak), <7 mg/L (trough). Desired serum concentrations: 5–10 mg/L (peak), <2 mg/L (trough). 6 >28 wk Dose 15 20 15 10 15 Frequency q12h q24h q24h q24h q48h Serum creatinine concentrations normally fluctuate and are partly influenced by transplacental maternal creatinine in the first week of age.
2015 Nelson's Pediatric Antimicrobial Therapy by John S. Bradley, John D. Nelson et al. (eds.)